本篇代写assignment-细胞毒性讲了细胞毒性是治疗药物对宿主细胞具有毒性的特征。这种细胞毒性被用来确定所提供的治疗的疗效。研究分析发现纳米颗粒具有一定的细胞毒性[12]。这种细胞毒性需要管理和了解，以开发强大的药物。治疗指数可用于评估每个纳米颗粒[12]的细胞毒性水平。本篇代写assignment文章由新西兰第一论文 Assignment First辅导网整理，供大家参考阅读。
Cytotoxicity is the characteristic feature of therapeutic medicines being toxic to the host cells. This cytotoxicity is determined to determine the efficacy of the therapy provided. From research analysis it is found that nanoparticles are found to have a certain level of cytotoxicity [12]. This cytotoxicity needs to be managed and understood to develop robust medication. Therapeutic index can be used to assess the cytotoxic levels of each nanoparticle [12]. Therapeutic index is the ratio of therapeutic effect to toxicity. It is imperative that there are low cytotoxic levels and high therapeutic effects to maintain healthy levels of therapeutic index. This is the fundamental factor that needs to be considered when considering developing nanomedicine. While developing targeted drug delivery through nanomedicine, it has been found that the cytotoxicity of the nano materials proves to be an impediment to the delivery of the drug. In simplistic terms there is a need to measure the cytotoxic drug delivery [9]. Some of the cytotoxic materials impede the normal mechanism of the cells or they prevent proliferation of the targeted cells [12]. Basically there should be an understanding of these mechanisms and a tangible method of measuring to ensure that there is proper delivery of these cells. This would enable the researchers to develop a robust drug delivery system. A number of initiatives have been taken to measure the cell cytotoxic levels of the anti-cancer drugs. Usage of formazen dyes, protease biomarkers and measuring the ATP content is used to measure cell toxicity [13].
Hence cytotoxicity, drug life and BBB prove to be the major factors that impede the effect of the nanomedicine. There have been a number of proposed solutions that are being clinically researched. The drug life, cytotoxicity and BBB factors are addressed in detail. These are tabulated in the figure below. Few examples have been proposed in the table below. There are several more factors and researches that have been undertaken in the recent times to combat this issue.
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