可以發現，腎上腺素和去甲腎上腺素的親和力與α- 1和α- 2的親和力相同。然而，在其他一些情況下，我發現其中一種藥物的親和力比受體高得多(Peuler et al . 625)。這些在價值親和力上的差異已經完全被用來將受體亞分類為兩種不同類型。研究發現，腎上腺素在α- 1受體中與β- 2的結合具有較高的親和力。因此，可以理想化地認為，腎上腺素對平滑肌的影響是由於對alpha1和beta2受體的相對親和力依賴性較低。當腎上腺素濃度較低時，可導致β- 2受體的選擇性刺激。因此，當腎上腺素濃度增加時，可能存在血管收縮的主要影響。
Beta-adrenoceptors helps in the process of binding the receptors which are on the smooth muscle tissues. Beta-adrenoceptor use is generally released by the sympathetic androgenic stimulation. Another effect of the same is that it can lead to the harms in the nodal tissue and the conducting systems. These also lead to the binding of both the norepinephrine and epinephrine which may be circulating in the blood. The receptors may also be exhibiting the set of responses which may prove to be the different from those of α receptors. These are the ones that may be characterized because of its response to isoproterenol in the body. It may be considered to use the proper psychological responses to the process of adrenergic stimulation as per the kind of situations. There may be stimulations of the same.
It can be found that affinity for Epinephrine and norepinephrine is same as that of the affinity of alpha1 and alpha2. Though, in some other instances I have been found that the affinity of one of the drug had been much higher in comparison to that of the receptor (Peuler et al 625). These kinds of differences in the value affinity had been completely used for the sub classification of the receptors into the two different types. It has been found that epinephrine generally has a higher value of affinity related to the beta2 settle in some of the alpha1 receptors. Thus, it can be idealized that the impact of epinephrine on the smooth muscles is because of the lower dependence on the relative affinity which may be there for the alpha1 and beta2 receptors. Whenever the concentration of epinephrine is lower, it can lead to the selective stimulation of the beta2 receptors. Thus, when the concentration of epinephrine increases, there may be a predominant impact of vasoconstriction.